The Burden of Metabolic Syndrome on Osteoarthritic Joints

Bruce M. Dickson; Anke J. Roelofs; Justin J. Rochford; Heather M. Wilson; Cosimo De Bari


Arthritis Res Ther. 2019;21(289) 

In This Article


A literature review was conducted through an electronic search of MEDLINE and PubMed search engines to identify relevant papers using the following keywords: osteoarthritis, obesity, metabolic syndrome, hyperglycaemia, hypertension, infrapatellar fat pad, macrophage, and chondrocyte. Further electronic searches were conducted for specific proteins of interest that emerged from the initial searches. Additional references were identified from reference lists to supplement electronic searching. Final references for inclusion were selected to provide substantial coverage of the reviewed topics, whilst adhering to the editorial guidelines regarding the number of citations.