Quantifying Heart Failure Using Natriuretic Peptides May Help the HEART Teamin Decision-making

Eleni Michou; Gregor Fahrni; Christian Mueller


Eur Heart J. 2019;40(41):3406-3408. 

In This Article

Can a Blood Test Quantify HF?

BNP and NT-proBNP are secreted from the heart in response to pressure and/or volume overload. Accordingly, they are inexpensive, widely available, non-invasive tools to quantify haemodynamic stress and HF. As such, BNP and NT-proBNP measurements are recommended with a class IA recommendation as an aid to clinicians for the diagnosis of HF in patients with acute dyspnoea and/or suspected HF.[6,7] In addition, they have been proposed as attractive screening tools for the detection of subclinical disease in high-risk populations (e.g. diabetic and hypertensive patients), as well as prognostic and risk stratification tools in patients with cardiovascular diseases and in the pre-operative setting.[8] Recently, BNP concentration was also reported as a stronger predictor of mortality than traditional risk factors in the general population irrespective of the clinical HF status.[9]