Acellular Fish Skin Graft use for Diabetic Lower Extremity Wound Healing

A Retrospective Study of 58 Ulcerations and a Literature Review

Shannon Michael, DPM; Christopher Winters, DPM; Maliha Khan, DPM


Wounds. 2019;31(10):262-268. 

In This Article


The results of this 3-year retrospective study support increased wound healing rates with the use of acellular fish skin graft for treatment of DFUs. Furthermore, rapid wound surface area reduction during the initial 4 weeks following graft application corroborates previous research[10,13] that acellular fish skin graft enables the DFU to transition from a chronic inflammatory stage to an acute wound environment for healing.