Sub-hypnotic Dose of Propofol as Antiemetic Prophylaxis Attenuates Intrathecal Morphine-induced Postoperative Nausea and Vomiting, and Pruritus in Parturient Undergoing Cesarean Section

A Randomized Control Trial

Sylvanus Kampo; Alfred Parker Afful; Shiraj Mohammed; Michael Ntim; Alexis D. B. Buunaaim; Thomas Winsum Anabah


BMC Anesthesiol. 2019;19(177) 

In This Article


In conclusion, this study findings suggested that a sub-hypnotic dose of propofol could be as effective as metoclopramide in the prevention of PONV in parturient undergoing cesarean section under spinal anesthesia with intrathecal morphine. Also, a single sub-hypnotic dose of propofol may result in a low incident of opioid-induced pruritus. Therefore, propofol may be a better choice of antiemetic prophylaxis for opioid-induced PONV and pruritus in cesarean section.