Smoking Status and Cause-Specific Discontinuation of Tumour Necrosis Factor Inhibitors in Axial Spondyloarthritis

Sizheng Steven Zhao; Kazuki Yoshida; Gareth T. Jones; David M. Hughes; Stephen J. Duffield; Sara K. Tedeschi; Houchen Lyu; Robert J. Moots; Daniel H. Solomon; Nicola J. Goodson


Arthritis Res Ther. 2019;21(177) 

In This Article


Smokers commencing TNFi were no more likely to discontinue treatment than never smokers in this large UK cohort of axSpA participants. To better estimate causal effects of smoking exposure, future studies would benefit from recording more detailed smoking history, and exploring cause-specific treatment discontinuation in larger cohorts with clearer recording of reasons for discontinuation.