Packed Red Blood Cell Transfusion Associates With Acute Kidney Injury After Transcatheter Aortic Valve Replacement

Akeel M. Merchant; Javier A. Neyra; Abu Minhajuddin; Lauren E. Wehrmann; Richard A. Mills; Sarah K. Gualano; Dharam J. Kumbhani; Lynn C. Huffman; Michael E. Jessen; Amanda A. Fox


BMC Anesthesiol. 2019;19(99) 

In This Article


Transfusion of pRBCs but not nadir perioperative Hgb independently associated with post-TAVR AKI. Maximum concurrent number of administered inotropes and vasopressors during the post-TAVR period also independently associated with the development of post-TAVR AKI. Future studies are needed to explore the pathobiological mechanisms underlying these associations as well as to assess the impact of approaches such as pre-procedure anemia optimization and restrictive pRBC transfusion thresholds on the development of post-TAVR AKI.