A Comprehensive Review of Local Pharmacologic Therapy for Pyoderma Gangrenosum

David Baltazar, DPT; Carter Haag, BS; Angela S. Gupta, BSc; Angelo V. Marzano, MD; Alex G. Ortega Loayza, MD


Wounds. 2019;31(6):151-157. 

In This Article


The limitations of this review include the status of PG as a diagnosis of exclusion without reliable biological or laboratory markers for definitive diagnosis. There continues to be a need for development, reliability testing, and validation of a severity rating system for PG so that outcomes can be adjusted for PG severity or risk factors such as wound size, degree of inflammation, and pain. Due to the use of case reports in this review, there also is a lack of standardization when comparing treatments and patient response.