Conclusion
Our pilot randomized trial identified no statistically significant improvement in exercise capacity, symptoms or quality of life with pulmonary rehabilitation after exacerbations. This pilot data suggests that any benefits of pulmonary rehabilitation in this setting are likely to be too small to be clinically meaningful.
Abbreviations
6 MW: 6 min walking test; CAT: COPD assessment test; CI: Confidence intervals; COPD: Chronic obstructive pulmonary disease; CT: Computed tomograph; FEV1: Forced expiratory volume in 1 s; FVC: Forced vital capacity; IQR: Interquartile range; LCQ: Leicester cough questionnaire; PR: Pulmonary rehabilitation; SC: Standard care; SGRQ: St Georges Respiratory Questionnaire
Acknowledgements
Not applicable.
Funding
Tenovus Scotland. JDC is supported by the GSK/BLF Chair of Respiratory Research. The funders had no role in study design, interpretation or reporting.
Availability of data and materials
The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.
Ethics approval and consent to participate
The study was approved by the East of Scotland ethics committee and all patients gave written informed consent (13/ES/0062).
Consent for publication
Not applicable.
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Trial registration
NCT02179983, registered on Clinicaltrials.gov 29th June 2014.
BMC Pulm Med. 2019;19(85) © 2019 BioMed Central, Ltd.
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