Use of Ceftazidime-Avibactam in Infants and Children

Marcia L. Buck, PharmD, FCCP, FPPAG, BCPPS

Disclosures

Pediatr Pharm. 2019;25(5) 

In This Article

Drug Interactions

Avibactam is a substrate of organic ion transporters 1 and 3 (OAT1 and OAT3) which might contribute to its uptake and excretion.[2] Probenecid is a potent OAT inhibitor and may produce up to a 70% reduction in avibactam elimination when administered concomitantly.

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3090D553-9492-4563-8681-AD288FA52ACE

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