Computed Tomographic Imaging in Connective Tissue Diseases

Joseph Barnett, FRCR; Anand Devaraj, MD, MRCP, FRCR


Semin Respir Crit Care Med. 2019;40(2):159-172. 

In This Article


The accurate interpretation of HRCT in the context of CTD requires close radiological and clinical collaboration. As has been shown, some CT findings may be highly suggestive of the presence of a CTD. In a significant minority of patients, pulmonary disease represents the first manifestation of a CTD, and perhaps more commonly, the radiologist must interpret images in the absence of clinical data. In these circumstances, in addition to the earlier documented findings, the possibility of CTD should be raised by the involvement of multiple pulmonary compartments or the presence of an NSIP pattern of pulmonary fibrosis.