Rheumatoid Nodules in Thyroid Gland Parenchyma as an Expression of Rheumatoid Arthritis

A Case Report

Efthimios Sivridis; Maria Kouroupi; Michael Ioannis Koukourakis; Stella Arelaki; Nikolaos Lyratzopoulos; Alexandra Giatromanolaki


J Med Case Reports. 2019;13(159) 

In This Article

Abstract and Introduction


Background: The rheumatoid nodule is the most common extra-articular manifestation of rheumatoid arthritis. When present, it is readily identified in conventional hematoxylin and eosin sections.

Case presentation: We report a case with several rheumatoid nodules in a thyroid gland of a 33-year-old Greek woman with a 3-year history of rheumatoid arthritis treated with methotrexate, after having total thyroidectomy for hypothyroidism.

Conclusion: To the best of our knowledge, this is the first time that rheumatoid nodules have been encountered in the thyroid gland.