New Findings, Pathophysiology, and Antigen Analysis in Pollen-Food Allergy Syndrome

Akiko Yagami; Motohiro Ebisawa


Curr Opin Allergy Clin Immunol. 2019;19(3):218-223. 

In This Article


Major advances in the allergen analysis of PFAS have been achieved. By accurately diagnosing and identifying allergens, the severity of PFAS patients became possible to predict. However, pathogenesis and antigenicity have not yet been fully clarified yet, and progress would be expected in the future research. GRP has been a newly identified allergen distributed in various plants, such as vegetables and fruits. PFAS not only involves local oral allergic symptoms, but also can induce serious symptoms, such as anaphylaxis. It is hoped that advances in diagnostic techniques and antigen analysis will result in establishing effective therapeutic methods.