The Antiplaque/Anticariogenic Efficacy of Salvadora Persica (Miswak) Mouthrinse in Comparison to That of Chlorhexidine

A Systematic Review and Meta-analysis

Elaf Jassoma; Lina Baeesa; Heba Sabbagh


BMC Oral Health. 2019;19(64) 

In This Article

Conclusion and Recommendations

This meta-analysis and systematic review indicated clear antiplaque and anticariogenic effects of Salvadora persica extracts with a recommendation evidence of Ia and class A strength.[39] Although its effects are considered inferior to the gold standard chlorhexidine, it is still an effective antimicrobial that can be used as an alternative, especially for long-term use. Future high-quality randomized controlled clinical trials with larger sample sizes and longer follow-up periods are recommended, particularly in communities with low-income patients and medically compromised children. Additionally, different concentrations of Salvadora persica should be studied in-vivo in order to reach consensus about the most effective concentration of Salvadora persica to use for reducing different oral microbes.