Acute Kidney Injury, Chronic Kidney Disease, and Mortality: Understanding the Association

Melanie Meersch, MD


Anesth Analg. 2019;128(5):841-843. 

In This Article

Abstract and Introduction


Acute kidney injury is gaining more and more importance as a serious postoperative complication after surgical procedures. Assuming that 300 million surgical interventions are performed each year and 12%–47% develop an episode of acute kidney injury after surgery,[1,2] >36 million patients are affected by this critical condition annually. This elucidates the burden of the disease and demonstrates why serious effort needs to be performed in understanding the underlying pathophysiology and its consequences. Especially the comprehension of the interaction between acute kidney injury and chronic kidney disease and the repercussions on patients' outcomes bear further attention.