The Role of Bowel Preparation in Colorectal Surgery

Results of the 2012-2015 ACS-NSQIP Data

Aaron L. Klinger, MD; Heather Green, MS; Dominique J. Monlezun, MD, PhD, MPH; David Beck, MD; Brian Kann, MD; Herschel D. Vargas, MD; Charles Whitlow, MD; David Margolin, MD


Annals of Surgery. 2019;269(4):671-677. 

In This Article


Combined MBP and oral antibiotic bowel preparation significantly reduces infectious complications, including C. difficile colitis, after elective colon and rectum resections. MBP alone does not reduce infectious outcomes and oral antibiotics are not fully effective without a purged bowel. Combined preparation should be used before every elective colorectal resection unless otherwise contraindicated.