Premedication With Intranasal Dexmedetomidine Decreases Barbiturate Requirement in Pediatric Patients Sedated for Magnetic Resonance Imaging

A Retrospective Study

Panu Uusalo; Mirjam Lehtinen; Eliisa Löyttyniemi; Tuula Manner; Mika Scheinin; Teijo I. Saari


BMC Anesthesiol. 2019;19(22) 

In This Article


IN dexmedetomidine is an easily administered premedication agent or anesthetic adjuvant that appears to markedly reduce the requirement of barbiturates. Compared to sedation with thiopental alone, the use of IN dexmedetomidine as premedication may help to prevent respiratory depression. Further studies on the optimal dosage and delivery methods of IN dexmedetomidine for procedural MRI sedation appear as warranted.