Research on Indocyanine Green Angiography for Predicting Postoperative Hypoparathyroidism

Hao Jin; Qichao Dong; Zhuocheng He; Jinrui Fan; Kun Liao; Min Cui

Disclosures

Clin Endocrinol. 2019;90(3):487-493. 

In This Article

Results and Discussion

Visual and Fluorescence Imaging Scores

The set of study aimed to protect the parathyroid intraoperation and predict the postoperative parathyroid function. Table 1 provides the results obtained from the preliminary analysis of the clinical data and laboratory tests of the 26 participants. Table 2 and Figure 3 illustrates the visual and fluorescent imaging scores. Table 2 compares the experimental data between the visual scores and the ICG scores. There is a significant difference (P = 0.003) between the two groups. Visual scores were significantly higher than ICG angiography scores. In the patients that there was discordance between the visual and ICG scores, the parathyroid glands were autotransplanted.

Figure 3.

Fluorescence imaging scores and visual evaluation scores of parathyroid. A, ICG score 2; B, ICG score 1; C, ICG score 0; D, Visual score 2; E, Visual score 1; F, Visual score 0. Circles and arrows show parathyroid glands

Follow-up

In the 22 patients with at least one parathyroid gland with an ICG score of 2, postoperative PTH levels were in the normal range. In four patients, ICG angiography did not demonstrate a well vascularized parathyroid gland. Two of these patients developed transient hypoparathyroidism (PTH level 1.36 and 1.29 pmol/L on POD 1), with recovery on POD 7 for the first patient (PTH 3.6 pmol/L) and after 3 months for the second (PTH 3.8 pmol/L). Neither of these patients developed hypocalcaemia at the time of measurements.

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