Nicox Teams Up With Chinese Firm to Develop and Sell Glaucoma Drug

By Reuters Staff

December 18, 2018

PARIS (Reuters) - French ophthalmology company Nicox and Chinese firm Ocumension Therapeutics said on Monday they had signed an exclusive license agreement to develop and sell a yet-to-be approved Nicox drug to treat glaucoma in China.

The most commonly prescribed treatments for glaucoma include Pfizer's Xalatan, known generically as latanoprost, Novartis's Travatan (travoprost), and Allergan's Lumigan (bimatoprost).

Nicox, which already has a U.S-approved drug, Vyzulta (latanoprostene bunod), to treat glaucoma, is currently developing a second-generation product, NCX 470, for which it has entered in phase II clinical trials.

Under the terms of its agreement with Ocumension, Nicox is to receive royalties from 6-12 percent on net sales of NCX 470 in China. Ocumension is to conduct additional clinical studies for the regulatory approval of the drug in the country.

Nicox will also receive up to 36.25 million euros ($40.98 million) in development and commercial milestone payments, including a 3 million euro upfront payment.

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