Acute Respiratory Failure and Pulmonary Complications in End-Stage Liver Disease

Nida Qadir, MD; Tisha Wang, MD; Igor Barjaktarevic, MD, PhD; Steven Y. Chang, MD, PhD


Semin Respir Crit Care Med. 2018;39(5):546-555. 

In This Article

Management of Acute Respiratory Failure

Regardless of the etiology, the consequent development of acute respiratory failure in patients with ESLD has reported ICU mortality rates of 50 to 75%[56–60] and a 1-year mortality rate of 89%[58] when IMV is required. Cirrhosis is associated with worse outcomes in mechanically ventilated patients. Lai et al recently demonstrated that patients with cirrhosis requiring IMV had higher mortality than propensity-matched noncirrhotics on IMV.[59] In light of the high risk of death in these patients, appropriate management of acute respiratory failure is imperative.