Recurrent Optic Neuritis as the Only Manifestation of Chronic Hepatitis B Virus Flare

A Case Report

Diana Curras-Martin; Natasha Campbell; Attiya Haroon; Mohammad A. Hossain; Arif Asif


J Med Case Reports. 2018;12(316) 

In This Article


Retrobulbar optic neuritis in association with HBV is rarely the only manifestation of chronic hepatitis B flare. The recommended standard of care involves the use of systemic steroids. However, given the recurrence of HBV flare, the risk of worsening the hepatitis with a high-dose steroid is a reality. Consequently, our options were limited to antiviral therapy alone. Our patient successfully achieved a complete resolution of symptoms with improvement of his liver function after treatment with entecavir alone. Further studies are needed to establish the role of antiviral therapy alone in the management of optic neuritis encountered in the context of hepatitis flare.