Recurrent Optic Neuritis as the Only Manifestation of Chronic Hepatitis B Virus Flare

A Case Report

Diana Curras-Martin; Natasha Campbell; Attiya Haroon; Mohammad A. Hossain; Arif Asif


J Med Case Reports. 2018;12(316) 

In This Article


Autoimmune reactions are commonly encountered with acute hepatitis B virus infection. Vasculitis, glomerulonephritis, arthritis, and optic neuritis have all been described in the literature.[1] High levels of circulating immune complexes, tissue deposit, and complement activation support the pathophysiology.[2] Here, we present a case of recurrent optic neuritis associated with reactivation of chronic hepatitis B virus (HBV) flare, where the ocular symptoms constituted the chief complaint.