A High Risk of Sleep Apnea Is Associated With Less Postoperative Cognitive Dysfunction After Intravenous Anesthesia

Results of an Observational Pilot Study

Soeren Wagner; Joerg Quente; Sven Staedtler; Katharina Koch; Tanja Richter-Schmidinger; Johannes Kornhuber; Harald Ihmsen; Juergen Schuettler


BMC Anesthesiol. 2018;18(139) 

In This Article


In conclusion, this is the first prospective study that elicited indications for beneficial effects of possible intrinsic hypoxic preconditioning in patients suspected of being at high risk for OSAS on the early postoperative cognitive function. Focusing on memory function and work memory performance after anesthesia for non-cardiac surgery, we discovered significant differences between patients suspect to sleep apnea and control patients. In a clinical setting, the DemTect or SKT can be recommended to assess cognitive impairment in a fast and valid manner. Cognitive reserve and learning ability might play a role in compensating deficits in executive function. Further investigations are needed to address the impact of the anesthesia regimen.