Update: Influenza Activity — United States and Worldwide, May 20–October 13, 2018

Eric J. Chow, MD; C. Todd Davis, PhD; Anwar Isa Abd Elal; Noreen Alabi, MPH; Eduardo Azziz-Baumgartner, MD; John Barnes, PhD; Lenee Blanton, MPH; Lynnette Brammer, MPH; Alicia P. Budd, MPH; Erin Burns, MA; William W. Davis, DrPH; Vivien G. Dugan, PhD; Alicia M. Fry, MD; Rebecca Garten, PhD; Lisa A. Grohskopf, MD; Larisa Gubareva, PhD; Yunho Jang, PhD; Joyce Jones, MS; Krista Kniss, MPH; Stephen Lindstrom, PhD; Desiree Mustaquim, MPH; Rachael Porter, MPH; Melissa Rolfes, PhD; Wendy Sessions, MPH; Calli Taylor, MPH; David E. Wentworth, PhD; Xiyan Xu, MD; Natosha Zanders, MS; Jacqueline Katz, PhD; Daniel Jernigan, MD


Morbidity and Mortality Weekly Report. 2018;67(42):1178-1185. 

In This Article

Composition of the 2019 Southern Hemisphere Influenza Vaccine

The WHO recommendations for influenza vaccine composition for the Southern Hemisphere 2019 season were made at the WHO Consultation and Information Meeting on the Composition of Influenza Virus Vaccines held September 24–27, 2018, in Atlanta, Georgia. The recommended components for the 2019 Southern Hemisphere egg-based influenza trivalent vaccines are an A/Michigan/45/2015 (H1N1)pdm09-like virus, an A/Switzerland/8060/2017 (H3N2)-like virus, and a B/Colorado/06/2017-like virus (B/Victoria lineage). For egg-based quadrivalent vaccines, an additional component, B/Phuket/3073/2013-like virus (B/Yamagata lineage), is recommended. It was recommended that the A(H3N2) component of non–egg-based vaccines be an A/Singapore/INFIMH-16–0019/2016-like virus. Compared with the composition of the 2018 Southern Hemisphere influenza vaccine formulation, these recommendations reflect an update to the influenza A(H3N2) component for egg-based vaccines, a change in the influenza B lineage included in the trivalent vaccine and a change in the influenza B/Victoria component. Compared with the composition of the Northern Hemisphere 2018–19 influenza vaccines, these recommendations reflect only one change, an update to the A(H3N2) component used in egg-based manufacturing.