Negative Pressure Wound Therapy of Open Abdomen and Definitive Closure Techniques After Decompressive Laparotomy

A Single-Center Observational Prospective Study

Mircea Muresan, MD, PhD; Simona Muresan, MD, PhD; Klara Brinzaniuc, MD, PhD; Daniela Sala, MD, PhD; Radu Neagoe, MD, PhD


Wounds. 2018;30(10):310-316. 

In This Article


In the complex treatment of ACS, DL is a necessary therapeutic solution to improve prognosis. Decompressive laparotomy aims both to release the IAP and treat the underlying disease. The open abdomen management was based on eliminating secretions, protecting the viscera, and avoiding lateral musculoaponeurotic retraction. Negative pressure wound therapy was utilized in all cases, as recommended by the WSACS Guidelines of 2013.[1] Compared with the observational retrospective study group, NPWT increased the primary and definitive closure rate and reduced local complications and the number of days of hospitalization. The mortality rate was decreased (but not statistically significantly) due to the favorable effect of NPWT on the primary disease, thus eliminating the abdominal secretions and avoiding collections in the septic abdomen.