Focal Therapy of Prostate Cancer

Nicolai Hübner; Shahrokh F. Shariat; Mesut Remzi


Curr Opin Urol. 2018;28(6):550-554. 

In This Article


Focal therapy is usually considered to be the ablation of a visible index lesion of clinically significant cancer. In selected patients, focal therapy is well tolerated and efficacious. Side effects, such as erectile dysfunction and incontinence, occur less after focal therapy than after whole-gland treatment. Further trials, or analysis of large retrospective cohorts, are needed before long-term oncologic outcome can be properly assessed and focal therapy can be considered a standard treatment for localized PCa. At this point, however, patients who do fit into the criteria set for focal therapy can and should be offered to partake in a clinical trial involving focal therapy.