Ocular Allergy as a Risk Factor for Dry Eye in Adults and Children

Edoardo Villani; Giovanni Rabbiolo; Paolo Nucci


Curr Opin Allergy Clin Immunol. 2018;18(5):398-403. 

In This Article


In conclusion, ocular allergy and DED are two common, relevant, symptomatic, not mutually exclusive conditions affecting the ocular surface. They share some clinical and biochemical features.

If DED is a comprehensive term, including different types of patients, ocular allergy include a very wide spectrum of clinical conditions, ranging from mild-SAC-to-severe and sight-threatening keratoconjunctivitis.

Recent advances in the comprehension of DED pathogenic mechanisms allow identifying several pathways of interaction between these two conditions, providing a strong rationale to consider ocular allergy as a risk factor for DED (Figure 1).

Ocular allergy have peculiar implications and manifestations in children. Further studies on this topic will help to better understand the several outstanding issues relating to pediatric ocular surface and DED.