In conclusion, using dexmedetomidine as an adjuvant to bupivacaine for intrathecal analgesia in lower limb surgeries has longer duration of sensory and motor block, longer postoperative analgesia with low side effects. All three treatments had lower side effects with no difference between groups.
ANOVA: Analysis of variance; ASA: American Society of Anesthesiologist; BD: Bupivacaine + Dexmedetomidine; BF: Bupivacaine + fentanyl; BN: Bupivacaine + normal saline; ECG: Electrocardiogram; HR: Heart rate; NIBP: Noninvasive blood pressure; NRS: Numeric Rating Scale; SBP: Systolic blood pressure; SPSS: Statistical Package for the Social Sciences
The authors would like to thank Rasoul-e-Akram Clinical Research Development Center, Iran University of Medical Sciences for their technical support.
Availability of data and materials
The datasets used and/or analyzed during the current study are available from the corresponding author upon a reasonable request.
Ethics approval and consent to participate
The Ethical Committee of Iran University of Medical Sciences approved the study and written informed consents were obtained from all participants.
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IRCT registration number: IRCT2017041010599N15, 24 May 2017.
BMC Anesthesiol. 2018;18(62) © 2018 BioMed Central, Ltd.