UK Guidelines Quiz: Do You Know The Latest on Managing Lyme Disease?

Tim Locke


February 12, 2019

The 2019 guideline from NICE supports diagnosis and treatment of Lyme disease in patients with erythema migrans without first confirming a diagnosis with laboratory tests.

If this rash is not present then a combination of clinical assessment and serological testing should be used to guide diagnosis and treatment. However, the diagnosis should not be ruled out if tests are negative and where Lyme disease is highly suspected.

Oral doxycycline is recommended first line for patients aged 12 and over with erythema migrans and/or non-focal symptoms. Weight-related doses of doxycycline are recommended first line for children aged 9-12 with erythema migrans and/or non-focal symptoms, and weight-related doses of oral amoxicillin for children aged under 9 with erythema migrans and/or non-focal symptoms.

For patients with focal symptoms oral doxycycline, oral amoxicillin, or intravenous ceftriaxone, may be appropriate depending on individual circumstances and symptom presentation.


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