Drug Safety Warnings and Updates: October-December 2017

Teresa Rubio, PharmD


February 16, 2018

Editorial Collaboration

Medscape &

In This Article

Stavudine (Zerit®)

For more on this Drug Safety Labeling Change, click here and here.

For full prescribing information, click here.

Updated Boxed Warning

Fatal lactic acidosis has been reported in pregnant women who received the combination of ZERIT and didanosine with other antiretroviral agents. Coadministration of ZERIT and didanosine is contraindicated because of increased risk for serious and/or life-threatening events. Suspend treatment if clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity occur.