Chronic Cough: Evaluation and Management

Charlie Michaudet, MD; John Malaty, MD


Am Fam Physician. 2017;96(9):575-580. 

In This Article

Ace Inhibitor–Related Cough

ACE inhibitor–related cough has been reported in 5% to 35% of patients and is more common in women.[35] It may start within hours to months of the first dose. When the medication is discontinued, resolution of the cough should occur within one week to three months; this is the only way to determine if the ACE inhibitor is causing the cough.

Angiotensin receptor blockers are a good alternative to ACE inhibitors. However, if the patient has a strong indication, restarting the ACE inhibitor may be attempted; in some patients, the cough will not recur.[35] When considering ACE inhibitors as the cause of chronic cough, other common causes should also be investigated.