Pediatric Premedication: A Double-blind Randomized Trial of Dexmedetomidine or Ketamine Alone Versus a Combination of Dexmedetomidine and Ketamine

Hui Qiao; Zhi Xie; Jie Jia


BMC Anesthesiol. 2017;17(158) 

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In summary, the combination of dexmedetomidine and ketamine produces definite sedative effects that help children separate quietly from their parents and smoothly accept induction of anesthesia, and is associated with fewer perioperative adverse events. This premedication combination is thus a reasonable option for use in clinical practice.