Conclusions
Our RCT involving patients with acute ischemic stroke and dyslipidemia did not show any superiority of early statin therapy administered within 24 hours of admission versus delayed administration until the seventh day of admission to alleviate the degree of disability at 90 days after admission.
Acknowledgments
We are indebted to Yukari Matsunaga, Yoko Kai, and Michiyo Horie for their data management and Kunimi Takashima and Noriko Fujita for their project management.
Sources of Funding
This study was supported by Shionogi Co, Ltd and the representative of Shionogi participated into the design and the drafting the article, but the operation, data collection, and statistical analyses were solely conducted by the academic authors (Drs Yoshimura, Uchida, Daimon, and Morimoto).
Clinical Trial Registration:
URL: http://www.clinicaltrials.gov. Unique identifier: NCT02549846.
Stroke. 2017;48(11):3057-3063. © 2017 American Heart Association, Inc.