British Association of Dermatologists' Guidelines for the Management of Pemphigus Vulgaris 2017

K.E. Harman; D. Brown; L.S. Exton; R.W. Groves; P.J. Hampton; M.F. Mohd Mustapa; J.F. Setterfield; P.D. Yesudian

Disclosures

The British Journal of Dermatology. 2017;177(5):1170-1201. 

In This Article

Extracorporeal Photopheresis (Strength of Recommendation D, Level of Evidence 3)

Extracorporeal photopheresis is known to have immunomodulatory effects[216] and has been used in small numbers of patients with pemphigus;[217–222] there are no RCTs. In a recent case series, eight patients with pemphigus were treated with two to six cycles of extracorporeal photopheresis, resulting in complete remission in all but one case. Steroid doses could be tapered in all treated patients.[223]

Summary

Extracorporeal photopheresis could be considered in recalcitrant cases of PV where there has been failure to improve with more conventional therapy.

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