Radiological Case: Metastatic Endometrial Serous Carcinoma to the Breast

Tayson Lin; David Lin, MD; Ziying Zhang, MD; Biren A. Shah, MD


Appl Radiol. 2017;46(11):42-45. 

In This Article

Imaging Findings

CT with intravenous and oral contrast revealed a markedly enlarged uterus in concordance with the diagnosis of endometrial cancer (Figure 1). Shifting attention to the suspicious breast lesion, diagnostic mammogram revealed a round mass at the site of the palpable abnormality (Figure 2) and targeted ultrasound demonstrated a round hypoechoic mass with mild internal vascularity (Figure 3).

Figure 1.

CT image of the abdomen and pelvis with intravenous and oral contrast. Sagittal (A) and axial (B) studies showed an enlarged uterus consistent with the diagnosis of endometrial cancer. The endometrium was heterogeneously thickened, with regions of enhancement and necrosis. The endometrial cavity itself appears air filled. Several coarse calcifications are seen within the left lateral uterine body and may represent partially calcified uterine fibroids. Incidental finding includes bilateral ovarian cysts.

Figure 2.

Diagnostic mammogram images (A-F) reveal a round mass measuring 25 mm in the upper inner quadrant of the right breast posteriorly that corresponds to the patient's palpable abnormality (triangular marker).

Figure 3.

(A) Targeted ultrasound demonstrates a solid mass at the site of the mammographic and clinically palpable mass at 1 o'clock of the right breast at a distance of 7 cm from the nipple. This mass has a hypoechoic pattern, angular margins, and round shape. (B) Doppler flow revealed mild internal vascularity.