Hepatitis A Virus: Essential Knowledge and a Novel Identify-Isolate-Inform Tool for Frontline Healthcare Providers

Kristi L. Koenig, MD; Siri Shastry, MD; Michael J. Burns, MD


Western J Emerg Med. 2017;18(6):1000-1007. 

In This Article

Differential Diagnosis

The differential diagnosis for a patient presenting with symptoms of HAV virus infection is broad. It includes hepatitis B, C, D and E viruses. Other infections in which acute hepatitis sometimes manifests include Epstein-Barr virus, cytomegalovirus, yellow fever, disseminated herpes simplex, adenovirus, HIV infection, malaria, leptospirosis, syphilis, Rocky Mountain spotted fever, typhoid fever and Q fever.[47] Non-infectious causes of similar symptoms should also be considered, including drug-induced liver injury (e.g., from acetaminophen), Budd-Chiari syndrome, Amanita phalloides mushroom poisoning, and autoimmune hepatitis.[48]