Influenza A(H3N2) Virus in Swine at Agricultural Fairs and Transmission to Humans, Michigan and Ohio, USA, 2016

*Nasal swab or nasal wipe samples were collected from swine at the end of the fair. ILI, influenza-like illness; rRT-PCR, real-time reverse transcription PCR.

*Genomic constellations of 13 influenza A virus isolates from swine are organized by the 8 gene segments of the influenza A virus genome with HA categorized as derived from the 2010–11 human seasonal H3N2 virus (human-like H3) or the established swine lineage H3N2 (cluster IV-A). The 6 internal gene segments (PB2, PB1, PA, NP, M, NS) are classified as originating from either the 1998 triple-reassortant internal gene (trig) or influenza A(H1N1)pdm09 (pdm). All NA genes were descendants of the 2002 N2 lineage common among North American swine¹². HA, hemagglutinin; M, matrix; NA, neuraminidase; NP, nucleoprotein; NS, nonstructural protein; PA, polymerase acidic; PB, polymerase basic.

Authors and Disclosures

Andrew S. Bowman, Rasna R. Walia, Jacqueline M. Nolting, Amy L. Vincent, Mary Lea Killian, Michele M. Zentkovich, Joshua N. Lorbach, Sarah E. Lauterbach, Tavis K. Anderson, C. Todd Davis, Natosha Zanders, Joyce Jones, Yunho Jang, Brian Lynch, Marisela R. Rodriguez, Lenee Blanton, Stephen E. Lindstrom, David E. Wentworth, John Schiltz, James J. Averill and Tony Forshey

The Ohio State University, Columbus, Ohio, USA (A.S. Bowman, J.M. Nolting, M.M. Zentkovich, J.N. Lorbach, S.E. Lauterbach); US Department of Agriculture, Ames, Iowa, USA (R.R. Walia, A.L. Vincent, M.L. Killian, T.K. Anderson, J. Schiltz); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.T. Davis, N. Zanders, J. Jones, Y. Jang, B. Lynch, M.R. Rodriguez, L. Blanton, S.E. Lindstrom, D.E. Wentworth); Michigan Department of Agriculture and Rural Development, Lansing, Michigan, USA (J.J. Averill); Ohio Department of Agriculture, Reynoldsburg, Ohio (T. Forshey)

Address for correspondence
Andrew S. Bowman, The Ohio State University, Department of Veterinary Preventive Medicine, 1920 Coffey Rd, Columbus, OH 4310, USA; email: bowman.214@osu.edu

Dr. Bowman is an assistant professor at The Ohio State University, where he leads a team researching the ecology and epidemiology of influenza A virus in swine and avian populations. He and his team are working to control influenza A virus in swine populations and reduce influenza A virus transmission across the swine–human interface.