Maine Orthopaedic Review Challenge

Test Your Knowledge of Treating Fractures in Trauma Patients

Bruce F. Gomberg, MD; Brad J. Yoo, MD

Disclosures

August 24, 2017

Negative-pressure wound management comprises an open-pore sponge, a semiocclusive dressing, and a vacuum source. This closed-system construct over open wounds has many beneficial effects.[2] Macrodeformation of the soft tissues results in closure of the wound and minimizes wound loss of domain, making secondary closure more likely. The wound environment is similarly stabilized, which allows edema control and thermal insulation. Both of these factors help inhibit bacterial growth. Intracompartmental pressures are similarly decreased, owing to the vacuum effect upon the limb. On a microscopic level, cellular microdeformation effects fibroblast mechanotransduction that results in an improved angiogenic response and proliferation of granulation tissue.

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