St John's Wort (Hypericum Perforatum)- Induced Psychosis

A Case Report

Maria Ferrara; Francesco Mungai; Fabrizio Starace


J Med Case Reports. 2017;11(137) 

In This Article


To date, the evidence available regarding the safety profile of Hypericum in people with risk factors for psychosis is still insufficient and more systematic research is necessary; clinicians and health professionals in general should consider the risk of Hypericum precipitating psychosis. Moreover, since patients generally do not volunteer information about usage of alternative medicines, it is particularly important that physicians actively elicit herbal remedy use in their history taking, particularly in cases of sudden-onset of psychosis. Finally, cautioning patients on the haphazard use of herbal remedies, such as Hypericum, should be part of best practice in health care.