Hello. I'm Dr Arefa Cassoobhoy, a practicing internist and a medical editor for Medscape and WebMD. Welcome to Morning Report, our 1-minute news story for primary care.
Antibiotics and Risk for Spontaneous Abortion
In a study of 182,000 pregnant women, the use of certain antibiotics during early pregnancy was linked with a higher rate of miscarriage before 20 weeks. These antibiotics included quinolones, tetracyclines, sulfonamides, metronidazole, and macrolides (except erythromycin).
Antibiotics not associated with spontaneous abortion were penicillins and cephalosporins. Of note, nitrofurantoin also was not on the list. So it's a good option for urinary tract infections, one of the most common infections in pregnancy.
Now, the authors state that the severity of infection could be a confounding variable, but the message is still clear: While the overall danger is low, certain antibiotics are a safer choice for women of childbearing age.
For Medscape and WebMD, I'm Dr Arefa Cassoobhoy.
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Medscape Internal Medicine © 2017 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Which Antibiotics Should Be Avoided in Early Pregnancy? - Medscape - May 05, 2017.