Risk of Stroke and Recurrence After AF Ablation in Patients With an Initial Event-Free Period of 12 Months

Simon Kochhäuser, M.D.; Pouria Alipour, B.Sc.; Tanjah Haig-Carter, B.Sc.; Kathleen Trought, B.Sc.; Philip Hache, B.Sc.; Yaariv Khaykin, M.D.; Zaev Wulffhart, M.D.; Alfredo Pantano, M.D.; Bernice Tsang, M.D.; David Birnie, M.D.; Atul Verma, M.D.


J Cardiovasc Electrophysiol. 2017;28(3):273-279. 

In This Article

Clinical Implications

The results of our study indicate that patients with an AF/AT-free interval of at least 12 months after AF ablation have a low risk of stroke/TIA and justify further research on the safety of discontinuing OAC after successful AF ablation. Prospective, randomized studies, like the upcoming OCEAN trial (https://clinicaltrials.gov/ct2/show/NCT02168829), that will be including a similar patient population, will be needed to determine whether OAC can be safely stopped postablation or whether the risk of stroke remains high enough to justify long-term OAC continuation.