Combination of Paclitaxel and MG1 Oncolytic Virus as a Successful Strategy for Breast Cancer Treatment

Marie-Claude Bourgeois-Daigneault; Lauren Elizabeth St-Germain; Dominic Guy Roy; Adrian Pelin; Amelia Sadie Aitken; Rozanne Arulanandam; Theresa Falls; Vanessa Garcia; Jean-Simon Diallo; John Cameron Bell


Breast Cancer Res. 2016;18(83) 

In This Article


With the urgent need for novel strategies for breast cancer treatment, especially in patients with TNBC, which are refractory to the limited available treatment options, our work provides a rational alternative to improve outcomes. Our data demonstrate that the combination of PAC and MG1 is effective at controlling tumor progression. Because PAC is a standard of care for breast cancer treatment and MG1 is undergoing clinical testing, we believe the findings included in this study are of great importance and that the translation of this work to the clinic could be rapid.