Erectile Dysfunction, Metabolic Syndrome, and Cardiovascular Risks

Facts and Controversies

Edward Sanchez; Alexander W. Pastuszak; Mohit Khera


Transl Androl Urol. 2017;6(1):28-36. 

In This Article


ED is the most common male sexual dysfunction. Growing evidence has established that ED shares many risk factors with systemic conditions including CVD and the MetS. ED has been linked to CVD and is considered a potential harbinger of future cardiovascular events. Given this relationship, each encounter for ED should be viewed by healthcare providers as an opportunity to screen for CVD and other comorbid conditions that can significantly affect a man's overall health. Proper referral for additional testing should be pursued when warranted as well. While universally accepted screening guidelines do not yet exist, expert panel suggestions such as the Princeton III Consensus Conference provide an initial risk stratification method for men with ED. Further research on the relationship between ED, CVD and MetS is required. As our understanding of this link evolves, so should our approach to evaluating and treating patients presenting with ED.