Treatment of Parkinson's Disease Psychosis

Andrew Schleisman, PharmD Candidate 2017; Mikayla Spangler, PharmD, BCPS; Emily Knezevich, PharmD, BCPS, CDE

Disclosures

US Pharmacist. 2016;41(11):HS-20-HS-26. 

In This Article

Motor and Nonmotor Symptoms of PD

At its core, PD is characterized by four cardinal symptoms: bradykinesia, rigidity, resting tremor, and postural instability.[4] Along with these typical motor symptoms come many nonmotor symptoms with significant associated morbidity and mortality. These include autonomic dysfunction, disorders of sleep and wakefulness, cognitive dysfunction and dementia, mood disorders, and psychosis.[5] These nonmotor symptoms of PD are responsible for a significant proportion of hospitalizations, with psychosis reportedly accounting for 24% of hospital admissions in patients with PD.[6] This fact signifies the importance of properly managing patients with PD psychosis (PDP) on both an inpatient and an outpatient basis.[6]

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