Preoxygenation: Physiologic Basis, Benefits, and Potential Risks

Usharani Nimmagadda, MD; M. Ramez Salem, MD; George J. Crystal, PhD


Anesth Analg. 2017;124(2):507-517. 

In This Article

Technique of Preoxygenation

To provide effective preoxygenation, a methodical approach is necessary. The importance of preoxygenation with a tight-fitting mask should be explained to the patient beforehand. Once preoxygenation is initiated, EtO2 and FIO2 values should be monitored closely. If the EtO2 value does not increase as expected, the anesthesia provider may have to hold the mask with both hands and/or replace the mask with a better-fitting one. Whenever possible, the induction should not start until the EtO2 value approximates or exceeds 90%.