COMMENTARY

10 Tech Advances That Can Change Medicine

Disclosures

December 16, 2016

First CRISPR Genome Editing and Initiation of Clinical Trials

In China, on October 28, the first  patient treatment with CRISPR genome editing for lung cancer was performed by removing immune cells, editing them to engender heightened immune function (disabling PD-1), culturing the cells, and injecting them back into the patient.[3] More trials have been approved to start in the United States for cancer and there has been remarkable progress for a variety of monogenic diseases, such as sickle cell, with clinical trials to start soon ( Table ).[4]

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