How Important Is Concomitant DVT in Prognosis of Acute PE?

Samuel Z. Goldhaber, MD


June 27, 2016

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This is Dr Sam Goldhaber for the Clot Blog for on Medscape, speaking to you from the American College of Cardiology meeting in Chicago.

Today I'm going to discuss the results of an important meta-analysis of pulmonary embolism trials of patients who had suffered from acute pulmonary embolism.[1] These trials had in common an ascertainment for the presence or absence of concomitant deep vein thrombosis (DVT). Nine studies were found, and these encompass more than 8000 patients with pulmonary embolism.

It turned out that about half of the patients had concomitant DVT along with their pulmonary embolism. When mortality rates were checked—among the patients with pulmonary embolism plus DVT versus pulmonary embolism without DVT—it turned out that the patients who had pulmonary embolism plus concomitant DVT had a doubling of their mortality rate compared with patients who had pulmonary embolism alone. The mortality rate increased to about 6% with concomitant DVT, compared with about 3% without concomitant DVT.

This makes it perhaps more important, for prognostic reasons, for us to assess the presence or absence of concomitant DVT in patients with acute pulmonary embolism.

This is Dr Sam Goldhaber, signing off for the Clot Blog.


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