Endoscopic Advances and the Microbiome Featured at DDW 2016

Caroline Helwick

May 19, 2016

SAN DIEGO — A study on an endoscopically implanted duodenojejunal bypass liner for the treatment of diabetes in obese patients and other presentations on advanced endoscopic techniques will take the spotlight at the upcoming Digestive Disease Week (DDW) 2016.

The amount of endoscopy-related content at the meeting speaks to the expansion of advanced endoscopy. "Techniques once thought to be relegated only to surgery are now becoming more commonplace in the endoscopy suite," said John Vargo, MD, chair of the Department of Gastroenterology and Hepatology at the Cleveland Clinic's Digestive Disease and Surgery Institute, who is secretary of the American Society for Gastrointestinal Endoscopy (ASGE), one of the meeting cosponsors.

Also presented will be an international trial comparing endoscopic ultrasonography-guided gastroenterostomy with surgical gastrojejunostomy for malignant gastric outlet obstruction.

Dr John Vargo

The treatment of large polyps will be addressed in a topic forum on endoscopic resection, during which results from two long-term outcomes studies will be presented — one on endoscopic mucosal dissection and the other on endoscopic submucosal dissection. "We will have a comparison of both techniques in these tandem abstracts," Dr Vargo told Medscape Medical News.

Also during that topic forum, Australian investigators will describe their tool for predicting adenoma recurrence after colonic endoscopic mucosal resection.

"One of the most important issues we have in GI endoscopy today is how to optimize the reprocessing of our equipment," noted Dr Vargo. Among the more than a dozen clinical symposia at the meeting will be one dedicated to this. Update on Infections Related to Endoscope Reprocessing is sure to draw a crowd, he said.

A plenary session on the future of endoscopic research and clinical practice will feature a presentation on innovative research in GI endoscopy and two distinguished lectures from world-renowned experts.

Dr Maria Abreu

The spotlight will also be on the microbiome, which will be addressed through a mix of invited and abstract-based sessions, said Maria Abreu, MD, director of the Crohn's and Colitis Center and professor of medicine, microbiology, and immunology at the University of Miami, who is council chair of the American Gastroenterological Association (AGA), another of the meeting cosponsors.

In one session, gut microbiota from volunteers will be analyzed to illustrate current DNA sequencing methods, analytic tools, and the relevance and limitations of microbiome data to human health.

Also presented at the meeting will be results from a number of trials that could be practice-changing, Drs Vargo and Abreu report.

Among these will be studies on the use of the monoclonal antibody bezlotoxumab for the prevention of Clostridium difficile infection, the use of fecal microbiota transplantation in patients with ulcerative colitis, the use of a double-reprocessing protocol for the prevention of scope-associated infections, and the consumption of a low-residue diet for bowel prep.

The meeting — jointly sponsored by the AGA, the American Association for the Study of Liver Diseases (AASLD), the ASGE, and the Society for Surgery of the Alimentary Tract (SSAT) — will be easy to navigate for the 15,000 physicians, researchers, and academicians expected to attend.

"We took the trouble to map every single abstract — oral and poster — to one of 15 disease or research tracks," said Dr Abreu.

The color-coded mapping, along with an improved app, will help attendees plan their itinerary. Those who wish to focus on particular topics can locate all sessions and abstracts of interest at a glance, she explained.

Experts in topic areas have created "redacted" versions of everything in the key topic areas for ease of selection for the general gastroenterologist. And efforts were made to minimize overlapping themes to give attendees "more bang for the buck," she said.

Attendees interested in basic and translational sciences will find much of interest along the convention center's "basic science corridor," Dr Abreu pointed out, and in sessions especially geared toward their interests.

And for the unique needs of trainees, designated experts in various topic areas have recommended a number of sessions tailor-made for physicians new to the field.

Dr Vargo is a consultant for Paion Medical. Dr Abreu has disclosed no relevant financial relationships.

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