Chronic Hepatitis C Virus Infection, a New Cardiovascular Risk Factor?

Fanny Domont; Patrice Cacoub


Liver International. 2016;36(5):621-627. 

In This Article


Among the large number of extrahepatic manifestations related to chronic HCV infection, cardiovascular involvement has probably been underestimated. Recent studies showed increased risk of cardiovascular events in HCV-infected patients, i.e. cerebrovascular, cardiac and renal events regardless of the severity of the liver disease or the common cardiovascular risk factors. The beneficial effects of successful antiviral treatment found in some studies (sustained virological response) on the cardiovascular risk offer new opportunities, particularly with the emergence of new interferon-free combinations more effective and well tolerated. These data need to be confirmed in prospective studies dedicated to these issues and including extended follow-up.