Randomized Clinical Study

Partially Hydrolyzed Guar Gum (PHGG) Versus Placebo in the Treatment of Patients With Irritable Bowel Syndrome

E. Niv; A. Halak; E. Tiommny; H. Yanai; H. Strul; T. Naftali; N. Vaisman


Nutr Metab. 2016;13(10) 

In This Article


This prospective, randomized, double blind placebo-controlled study supports the administration of 6 g/day PHGG for IBS patients with an expected clinical effect on bloating and gasses. It demonstrates that prebiotic administration has a significant effect on the symptoms of such challenging clinical condition as IBS. This finding emphasizes the significance of gut microbiota in pathogenesis and treatment of IBS.