Lipofilling of the Breast Does Not Increase the Risk of Recurrence of Breast Cancer

A Matched Controlled Study

Steven J. Kronowitz, M.D.; Cosman Camilo; Mandujano, M.D.; Jun Liu, M.D., Ph.D.; Henry M. Kuerer, M.D., Ph.D.; Benjamin Smith, M.D.; Patrick Garvey, M.D.; Reshma Jagsi, M.D.; Limin Hsu, M.A.; Summer Hanson, M.D.; Vicente Valero, M.D.


Plast Reconstr Surg. 2016;137(2):385-393. 

In This Article


The results of this study showed no increase in rates of locoregional recurrence, systemic recurrence, or second breast cancer and support the oncologic safety of fat grafting in breast reconstruction. Although receipt of hormonal therapy did significantly increase the risk of locoregional recurrence of breast cancer in patients who received lipofilling compared with patients who did not receive lipofilling, the recurrence rates were low. Before withholding lipofilling as a reconstructive option for breast cancer patients receiving hormonal therapy, a randomized trial would most be appropriate to determine the true clinical significance.